Prof. Ranjit Vijayan, FHEA
Department of Biology, College of Science
United Arab Emirates University
PO Box 15551, Al Ain, Abu Dhabi
United Arab Emirates

Office: F1-0192
Lab: E3-1008
Phone: +971 3 713 6302
Fax: +971 3 713 4927
Email: ranjit.v[at]uaeu.ac.ae


Employment
2022-Present:Professor, Computational Biology/Bioinformatics, Department of Biology, United Arab Emirates University, UAE
2017-2022: Associate Professor, Computational Biology/Bioinformatics, Department of Biology, United Arab Emirates University, UAE
2011-2017: Assistant Professor, Computational Biology/Bioinformatics, Department of Biology, United Arab Emirates University, UAE
2009-2011: Postdoctoral Research Associate, Department of Biochemistry, University of Oxford, UK


Education
2004-2008: DPhil, Biochemistry and Life Sciences Interface Doctoral Training Centre, University of Oxford, UK
2013-2015: DipGrad, Management, London School of Economics and Political Science, University of London, UK
2001-2004: MSc (Distinction), Computer Science, University of Wales, UK
1996-2000: BEng (First class honours), Electrical & Electronic Engineering, Nanyang Technological University, Singapore


Research interests
Molecular dynamics simulations of biological macromolecules
Protein structure modeling
Structure based drug discovery
Cryptides and bioactive peptides
Genomics, transcriptomics, & pharmacogenomics
Genetics of inherited disorders
High-performance computing
Word cloud


Teaching
Graduate courses
Applications of Bioinformatics
Advanced Molecular Biology Techniques I
Genomics
Special Topics in Cellular and Molecular Biology
Advanced Topics in Cellular and Molecular Biology
Research Methods
Seminar II
Lab Rotations

Undergraduate courses
Basic Biology
General Genetics (Biology)
General Genetics (Food & Agriculture)
Computing & Data Analysis for Biology
Nucleic Acid Dynamics
Macromolecules: Structure, Function and Bioinformatics
Essences of Cellular and Molecular Biology
Scientific Research Skills
Research Project (Cellular and Molecular Biology)
Research Project (General Biology)
Seminar (General Biology)
Seminar (Cellular and Molecular Biology)


Publications
  1. Antony, P., Baby, B., Rahma, A., Samad, S.A., Al Dhaheri, Y., Vijayan R. (2024) Molecular insights into the inhibition of angiotensin-converting enzyme 1 by hemopressin peptides. Scientific Reports 14:28726. PMID: 39567621. DOI: 10.1038/s41598-024-78893-3
  2. Antony P., Baby B., and Vijayan R. (2024) Insights into the interaction between hemorphins and δ-opioid receptor from molecular modeling. Frontiers in Molecular Biosciences 11:1514759. DOI: 10.3389/fmolb.2024.1514759
  3. Jobe A., and Vijayan R. (2024) Orphan G protein-coupled receptors: the ongoing search for a home. Frontiers in Pharmacology 15:1349097. PMID: 38495099. DOI: 10.3389/fphar.2024.1349097
  4. Alhammadi, S.H.A., Baby, B., Antony, P., Jobe, A., Humaid, R.S.M., Alhammadi, F.J.A., Vijayan R. (2024) Modeling the binding of anticancer peptides and Mcl-1. International Journal of Molecular Sciences 25(12):6529. PMID: 38928234. DOI: 10.3390/ijms25126529
  5. Alderei, L., Alshkeili, N., Alnaqbi, D., Shehab, O.A., Vijayan R.* Souid, A.-K.* (2024) Premarital counseling on the alpha thalassemia allele HBA2:c.*94A>G. Thalassemia Reports 14:44–48. DOI: 10.3390/thalassrep14020006 (* - Corresponding authors)
  6. Antony P., Baby B., Jobe A., and Vijayan R. (2024) Computational modeling of the interactions between DPP IV and hemorphins. International Journal of Molecular Sciences 25(5):3059. PMID: 38474306. DOI: 10.3390/ijms25053059
  7. Baby B., Vijay D., Philip P.S., Alnuaimi A.A., Almansoori H.M., Areidat S.O., Khan G., Vijayan R.*, and Akhtar M.K.* (2023) Complete genome sequence of Vibrio gazogenes PB1: an estuarine bacterium capable of producing prodigiosin from starch or cellulose. Frontiers in Marine Science 10:1028319. DOI: 10.3389/fmars.2023.1028319(* - Corresponding authors)
  8. Antony P., Baby B., Ali A., Vijayan R.* and Al Jasmi F.* (2023) Interaction of glutathione with MMACHC arginine-rich pocket variants associated with cobalamin C disease: Insights from molecular modeling. Biomedicines 11(12):3217. PMID: 38137438. DOI: 10.3390/biomedicines11123217 (* - Corresponding authors)
  9. Aziz M.A., Sabeem M., Kutty M.S., Rahman S., Alneyadi M.K., Alkaabi A.B., Almeqbali E.S., Brini F., Vijayan R., and Masmoudi K. (2023) Enzyme stabilization and thermotolerance function of the intrinsically disordered LEA2 proteins from date palm. Scientific Reports 13:11878. PMID: 37482543. DOI: 10.1038/s41598-023-38426-w
  10. Jobe A., Antony P., Altabbal, S., Al Dhaheri, Y., and Vijayan R. (2023) Interaction of hemorphins with ACE homologs. Scientific Reports 13:3743. PMID: 36878973. DOI: 10.1038/s41598-023-30771-0
  11. Sultan-Alolama M.I., Amin, A., Vijayan R.*, and El-Tarabily K.A.* (2023) Isolation, Characterization, and comparative genomic analysis of bacteriophage Ec_MI-02 from pigeon feces infecting Escherichia coli O157:H7. International Journal of Molecular Sciences 24(11):9506. PMID: 37298457. DOI: 10.3390/ijms24119506 (* - Corresponding authors)
  12. Alneyadi A., Nizami Z.N., Aburawi H.E., Hisaindee S., Nawaz M., Attoub S., Ramadan G., Benhalilou N., Al Azzani M., Elmahi Y., Almeqbali A., Muhammad K., Eid A.H., Vijayan R. and Iratni R. (2023) Synthesis of new chromene derivatives targeting triple-negative breast cancer cells. Cancers 15(10):2682. PMID: 37345018. DOI: 10.3390/cancers15102682
  13. Ajayi F.F., Mudgil P., Jobe A., Antony P., Vijayan R., Gan C.Y., Maqsood S. (2023) Novel plant-protein (quinoa) derived bioactive peptides with potential anti-hypercholesterolemic activities: Identification, characterization and molecular docking of bioactive peptides. Foods 12(6):1327. PMID: 36981252. DOI: 10.3390/foods12061327
  14. Antony P., Jobe A., and Vijayan R. (2022) Dynamics of the interaction between the receptor-binding domain of SARS-CoV-2 Omicron (B.1.1.529) variant and human angiotensin-converting enzyme 2. PeerJ 10:e13680. PMID: 35811809. DOI: 10.7717/peerj.13680
  15. Antony P., Baby B., Aleissaee H.M., and Vijayan R. (2022) A molecular modeling investigation of the therapeutic potential of marine compounds as DPP-4 inhibitors. Marine Drugs 20(12):777. PMID: 36547924. DOI: 10.3390/md20120777
  16. Vijay D., Baby B., Alhayer M.S., Vijayan R.*, and Akhtar M.K.* (2022) Native production of prodigiosin in the estuarine bacterium, Vibrio gazogenes PB1, and identification of the associated pig genes. Frontiers in Marine Science 9:940888. DOI: 10.3389/fmars.2022.940888 (* - Corresponding authors)
  17. Sultan-Alolama M.I., Amin, A., El-Tarabily K.A., and Vijayan R. (2022) Characterization and genomic analysis of Escherichia coli O157:H7 phage UAE_MI-01 isolated from birds. International Journal of Molecular Sciences 23(23):14846;. PMID: 36499178. DOI: 10.3390/ijms232314846
  18. Ali A., Soman S.S., and Vijayan R. (2022) Dynamics of camel and human hemoglobin revealed by molecular simulations. Scientific Reports 12(1):122. PMID: 34997093. DOI: 10.1038/s41598-021-04112-y
  19. Perveen N., Muzaffar S.B., Vijayan R., and Al-Deeb M.A. (2022) Assessing temporal changes in microbial communities in Hyalomma dromedarii collected from camels in the UAE using high-throughput sequencing. Frontiers in Veterinary Science 9:861233. PMID: 35433895. DOI: 10.3389/fvets.2022.861233
  20. Khasawneh M.A., AlKaabi A., Samadi A., Antony P., Vijayan R., Al-Keridis L.A., Saadeh H.A., Abutaha N. (2022) Synthesis and biological applications of some novel 8-hydroxyquinoline urea and thiourea derivatives. Arabian Journal of Chemistry 15(7):103905. DOI: 10.1016/j.arabjc.2022.103905
  21. Perveen N., Muzaffar S.B., Vijayan R., and Al-Deeb M.A.(2022) Microbial composition in Hyalomma anatolicum collected from livestock in the United Arab Emirates using next-generation sequencing. Parasites & Vectors 15:30. PMID: 35057842. DOI: 10.1186/s13071-021-05144-z
  22. Jobe A., and Vijayan R. (2021) Characterization of peptide binding to the SARS-CoV-2 host factor neuropilin. Heliyon 7(10):e08251. PMID: 34722943. DOI: 10.1016/j.heliyon.2021.e08251
  23. Alsamri, M.T., Alabdouli, A., Iram, D., Alkalbani, A.M., Almarzooqi, A.S., Souid, A.-K., and Vijayan R. (2021) A study on the genetics of primary ciliary dyskinesia. Journal of Clinical Medicine 10(21):5102. PMID: 34768622. DOI: 10.3390/jcm10215102
  24. Antony P., and Vijayan R. (2021) Role of SARS-CoV-2 and ACE2 variations in COVID-19. Biomedical Journal 44(3):235-244. PMID: 34193390. DOI: 10.1016/j.bj.2021.04.006
  25. Awang T., Chairatana P., Vijayan R.*, and Pongprayoon P.* (2021) Evaluation of the binding mechanism of human defensin 5 in a bacterial membrane: A simulation study. International Journal of Molecular Sciences 22(22):12401. PMID: 34830284. DOI: 10.3390/ijms222212401 (* - Corresponding authors)
  26. Jobe A., and Vijayan R. (2021) Neuropilins: C-end rule peptides and their association with nociception and COVID-19. Computational and Structural Biotechnology Journal 19:1889-1895. PMID: 33815686. DOI: 10.1016/j.csbj.2021.03.025
  27. Antony P., and Vijayan R. (2021) Dynamics of the interaction between angiotensin converting enzyme 2 and spike protein receptor binding domain of the SARS-CoV-2 B.1.617 variant. Biomolecules 11(8):1244. PMID: 34439910. DOI: 10.3390/biom11081244
  28. Antony P., and Vijayan R. (2021) Bioactive peptides as potential nutraceuticals for diabetes therapy: A comprehensive review. International Journal of Molecular Sciences 22(16):9059. PMID: 34445765. DOI: 10.3390/ijms22169059
  29. Vijayan R. (2021) Teaching and learning during the COVID-19 pandemic: A topic modeling study. Education Sciences 11(7):347. DOI: 10.3390/educsci11070347
  30. Alsamri M.A., Alabdouli A., Alkalbani A.M., Iram D., Tawil M.I., Antony P., Vijayan R.* and Souid A.-K.* (2021) Genetic variants of small airways and interstitial pulmonary disease in children. Scientific Reports 11:2715. PMID: 33526882. DOI: 10.1038/s41598-021-81280-x (* - Corresponding authors)
  31. Yahya A.M., Al-Hammadi S., AlMulla A.A., AlRufaye H.J., Al Dhaheri A., Elomami A.S., Kailas L., Vijayan R.*, and Souid A.-K* (2021) A case of leukocyte adhesion deficiency, type III presenting with impaired platelet function, lymphocytosis and granulocytosis. Frontiers in Pediatrics 9:713921. PMID: 34485203. DOI: 10.3389/fped.2021.713921 (* - Corresponding authors)
  32. Ayoub M.A., and Vijayan R. (2021) Hemorphins targeting G protein-coupled receptors. Pharmaceuticals 14(3):225. PMID: 33799973. DOI: 10.3390/ph14030225
  33. Ali A., Almesmari F.S.A, Al Dhahouri N., Ali A.M.S., Aldhanhani M.A.A.M.A, Vijayan R., Al Tenaiji A., Al Shamsi A., Hertecant J., and Al Jasmi F. (2021) Clinical, biochemical, and genetic heterogeneity in glutaric aciduria type II patients. Genes 12(9):1334. PMID: 34573316. DOI: 10.3390/genes12091334
  34. Sultan-Alolama M.I., El-Tarabily K.A., and Vijayan R. (2021) Complete genome sequence of Escherichia coli O157:H7 phage UAE_MI-01 isolated from bird feces. Microbiology Resource Announcements 10:e00348-21. PMID: 34264095. DOI: 10.1128/MRA.00348-21
  35. Fan S., Nedev H., Vijayan R., Iorga B.I., and Beckstein O. (2021) Precise force-field-based calculations of octanol-water partition coefficients for the SAMPL7 molecules. Journal of Computer-Aided Molecular Design 35:853–870 . PMID: 34232435. DOI: 10.1007/s10822-021-00407-4
  36. Yahya A.M., Al-Hammadi S., AlHashaykeh N.O., Alkaabi S.S., Elomami A.S., AlMulla A.A., Alremeithi M.M., Kabbary R.M., Vijayan R., and Souid A.-K. (2021) Case Report: Reactive lymphohistiocytic proliferation in infant with a novel nonsense variant of IL2RG who received BCG vaccine. Frontiers in Pediatrics 9:713924. PMID: 34796149. DOI: 10.3389/fped.2021.713924
  37. Al-Hammadi S., Yahya A.M., Al-Amri A, Shibli A, Balhaj G.B., Tawil M.I., Vijayan R., and Souid A.-K. (2021) Case Report: BCG-triggered hemophagocytic lymphohistiocytosis in an infant with X-linked recessive Mendelian susceptibility to mycobacterial disease due to variant of chronic granulomatous disease. Frontiers in Pediatrics 9:687538. PMID: 34268280. DOI: 10.3389/fped.2021.687538
  38. AlSamri H., El Hasasna H., Baby B., Alneyadi A., Al Dhaheri Y., Ayoub M.A., Eid A.H., Vijayan R., and Iratni R. (2021) Carnosol is a novel inhibitor of p300 acetyltransferase in breast cancer. Frontiers in Oncology 11:664403. PMID: 34055630. DOI: 10.3389/fonc.2021.664403
  39. Baba W.N., Mudgil P., Baby B.,Vijayan R., Gan C.-Y., and Maqsood S. (2021) New insights into the cholesterol esterase- and lipase-inhibiting potential of bioactive peptides from camel whey hydrolysates: Identification, characterization, and molecular interaction. Journal of Dairy Science 104(7):P7393-7405. PMID: 33934858. DOI: 10.3168/jds.2020-19868
  40. Jobe A., Baby B., Ali A., Vijayan R. (2021) Identification of potential anti-obesity drug scaffolds using molecular modeling. International Journal of Computational Biology and Drug Design 14(2):103-129. 10.1504/IJCBDD.2021.115674
  41. Baba W.N., Baby B., Mudgil P., Gan C.-Y., Vijayan R.* and Maqsood S.* (2021) Pepsin generated camel whey protein hydrolysates with potential antihypertensive properties: Identification and molecular docking of antihypertensive peptides. LWT - Food Science and Technology 143:111135. DOI: 10.1016/j.lwt.2021.111135 (* - Corresponding authors)
  42. Almarzooqi F.*, Souid A.-K.*, Vijayan R.*, and Al Hammadi S. (2021) Novel genetic variants of inborn errors of immunity. PLoS ONE 16(1): e0245888. PMID: 33481921. DOI: 10.1371/journal.pone.0245888. (* - Equal contribution)
  43. Alhefeiti M.A, Athamneh K., Vijayan R. and Ashraf S.S.(2021) Bioremediation of various aromatic and emerging pollutants by Bacillus cereus sp isolated from petroleum sludge. Water Science and Technology 83(7):1535-1547. PMID: 33843741. DOI: 10.2166/wst.2021.065
  44. Ali A., Johnstone E.K.M., Baby B., See H.B., Song A., Rosengren K.J., Pfleger K.D.G., Ayoub M.A., Vijayan R. (2021) Insights into the interaction of LVV-hemorphin-7 with angiotensin II type 1 receptor. International Journal of Molecular Sciences 22(1):209. PMID: 33379211. DOI: 10.3390/ijms22010209
  45. Ali A., and Vijayan R. (2020) Dynamics of the ACE2–SARS-CoV-2/SARS-CoV spike protein interface reveal unique mechanisms. Scientific Reports 10:14214. PMID: 32848162. DOI: 10.1038/s41598-020-71188-3
  46. Aljasmi F.A.*, Vijayan R.*, Sudalaimuthuasari N., Souid A.-K., Karuvantevida N., Almaskari R., Mohammed Abdul Kader H., Kundu B., Michel Hazzouri K., and Amiri K.M.A. (2020) Genomic landscape of the mitochondrial genome in the United Arab Emirates native population. Genes 11(8):876. PMID: 32752197. DOI: 10.3390/genes11080876 (* - Equal contribution)
  47. Perveen N., Muzaffar S.B., Vijayan R, and Al-Deeb M.A.(2020) Microbial communities associated with the camel tick, Hyalomma dromedarii: 16S rRNA gene-based analysis. Scientific Reports 10:17035. PMID: 33046763. DOI: 10.1038/s41598-020-74116-7
  48. Alsamri M.T., Alabdouli A., Alkalbani A.M., Iram D., Antony P., Vijayan R., and Souid A.-K. (2020) Genetic variants in children with chronic respiratory diseases. Pediatric Pulmonology. 55(9):2389-2401. PMID: 32662942. DOI: 10.1002/ppul.24908
  49. Ali A., Alzeyoudi S.A.R., Almutawa S.A., Alnajjar A.N., Al Dhaheri Y., and Vijayan R. (2020) Camel hemorphins exhibit a more potent angiotensin-I converting enzyme inhibitory activity than other mammalian hemorphins: an in silico and in vitro study. Biomolecules 10(3):486. PMID: 32210030. DOI: 10.3390/biom10030486
  50. Ali A., Alzeyoudi S.A.R., Almutawa S.A., Alnajjar A.N., and Vijayan R. (2020) Molecular basis of the therapeutic properties of hemorphins. Pharmacological Research 150:104855. PMID: 32438036. DOI: 10.1016/j.phrs.2020.104855
  51. Antony P., Baby B., Al Homedi Z., Al Halabi W., Ali A., and Vijayan R. (2020) Polypharmacological potential of natural compounds against prostate cancer explored using molecular docking and molecular dynamics simulations. International Journal of Computational Biology and Drug Design 13(2):181-199. DOI: 10.1504/IJCBDD.2020.107314
  52. Ali A., Baby B., Soman S.S., and Vijayan R. (2019) Molecular insights into the interaction of hemorphin and its targets. Scientific Reports 9(1):14747. PMID: 31611567. DOI: 10.1038/s41598-019-50619-w
  53. Ali A., Palakkott A., Ashraf A., Al Zamel I., Baby B., Vijayan R.*, and Ayoub M.A.* (2019) Positive modulation of angiotensin II type 1 receptor–mediated signaling by LVV–hemorphin-7 Frontiers in Pharmacology 10:1258. PMID: 31708782. DOI: 10.3389/fphar.2019.01258 (* - Corresponding authors)
  54. Almheiri M., Sanqoor S., Haidar M., Nazir M., and Vijayan R. (2019) Study of insertion-deletion polymorphisms (indels) in the UAE population. Forensic Science International: Genetics Supplement Series 7(1):P561-563. DOI: 10.1016/j.fsigss.2019.10.090
  55. Mudgil P., Baby B., Kamal H., Ngoh Y-Y, Vijayan R., Yuen G.C., and Maqsood S. (2019) Identification and molecular docking study of novel cholesterol esterase inhibitory peptides from camel milk proteins. Journal of Dairy Science 102(12):10748–10759. PMID: 31548068. DOI: 10.3168/jds.2019-16520
  56. Mudgil P., Baby B., Kamal H., Ngoh Y-Y, Vijayan R., Yuen G.C., and Maqsood S. (2019) Molecular binding mechanism and identification of novel antihypertensive peptides from camel milk protein hydrolysates. LWT - Food Science and Technology 112 (2019) 108193. DOI:10.1016/j.lwt.2019.05.091
  57. Ali A., Baby B., and Vijayan R. (2019) From desert to medicine: A review of camel genomics and therapeutic products. Frontiers in Genetics 10:17. PMID: 30838017. DOI:10.3389/fgene.2019.00017
  58. Baicharoen A., Vijayan R.* and Pongprayoon P.* (2018) Structural insights into betaine aldehyde dehydrogenase (BADH2) from Oryza sativa explored by modeling and simulations. Scientific Reports 8(1):12892. PMID:30150624. DOI:10.1038/s41598-018-31204-z
  59. Baby B., Antony P., and Vijayan R. (2018) Antioxidant and anticancer properties of berries. Critical Reviews in Food Science and Nutrition 58(15):2491-2507. PMID:28609132. DOI:10.1080/10408398.2017.1329198
  60. Al Hefeiti M.A., Mafofo J., Xavier G.T., Ramaswamy S., Baby B., Harilal D., Vijayan R., and Ashraf S.S. (2018) Draft genome sequence of Bacillus cereus strain UAEU- H3K6M1, a bacterium with potential bioremediation abilities, isolated from petroleum sludge. Microbiology Resource Announcements 7(3):e00856-18. DOI:10.1128/MRA.00856-18
  61. Prabakaran A.D., Karakkat J.V., Vijayan R., Chalissery J., Ibrahim M.F., Kaimala S., Adeghate E.A., Al-Marzouqi A.H., Ansari S.A., Epk M.B., and Emerald B.S. (2018) Identification of early indicators of altered metabolism in normal development using a rodent model system. Disease Models & Mechanisms 11(3). pii: dmm031815. PMID:29434026. DOI:10.1242/dmm.031815
  62. Al-Jezawi N.K., Al-Shamsi A.M., Suleiman J., Ben-Salem S., John A., Vijayan R., Ali B.R., Al-Gazali L. (2018) Compound heterozygous variants in the multiple PDZ domain protein (MPDZ) cause a case of mild non-progressive communicating hydrocephalus. BMC Medical Genetics 19(1):34. PMID:29499638. DOI:10.1186/s12881-018-0540-x
  63. Baby B., Antony P., and Vijayan R. (2018) Interactions of quercetin with receptor tyrosine kinases associated with human lung carcinoma. Natural Product Research 32(24):2928-2931. PMID:29022361. DOI:10.1080/14786419.2017.1385015
  64. Antony P., Baby B., and Vijayan R. (2016) Molecular insights into the binding of phosphoinositides to the TH domain region of TIPE proteins. Journal of Molecular Modeling 22(11):272. PMID:27783229. DOI:10.1007/s00894-016-3141-7
  65. Antony P., Baby B., Al Halabi, W., Al Homedi Z. and Vijayan R. (2016) Structural insights into the polypharmacological activity of quercetin on serine/threonine kinases. Drug Design, Development and Therapy 10:3109-3123. PMID:27729770. DOI:10.2147/DDDT.S118423
  66. Antony P., and Vijayan R. (2016) Acetogenins from Annona muricata as potential inhibitors of antiapoptotic proteins: a molecular modeling study. Drug Design, Development and Therapy 10:1399-1410. PMID:27110097. DOI: 10.2147/DDDT.S103216
  67. Antony P., and Vijayan R. (2015) Identification of novel aldose reductase inhibitors from spices: A molecular docking and simulation study. PLoS ONE 10(9):e0138186. PMID:26384019. DOI: 10.1371/journal.pone.0138186
  68. Mazzaferro S., Gasparri F., New K., Alcaino C., Faundez M., Iturriaga P., Vijayan, R., Biggin P.C., and Bermudez I. (2014) Non-equivalent ligand selectivity of agonist sites in (α4β2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy. Journal of Biological Chemistry 289:21795-217806. PMID:24936069. DOI: 10.1074/jbc.M114.555136
  69. Moroni M., Biro I., Giugliano M., Vijayan R., Biggin P.C., Beato M., and Sivilotti L.G. (2011) Chloride ions in the pore of glycine and GABA channels shape the time course and voltage dependence of agonist currents. Journal of Neuroscience 31:14095-14106. PMID:21976494. DOI: 10.1523/jneurosci.1985-11.2011
  70. Mazzaferro S., Benallegue N., Carbone A., Gasparri F., Vijayan R., Biggin P.C., Moroni M. and Bermudez I. (2011) Additional acetylcholine (ACh) binding site at α4/α4 interface of (α4β2)2α4 nicotinic receptor influences agonist sensitivity. Journal of Biological Chemistry 286:31043-31054. PMID:21757735. DOI: 10.1074/jbc.M111.262014
  71. Vijayan R., Sahai M.A., Czajkowski T., and Biggin P.C. (2010) A comparative analysis of the role of water in the binding pockets of ionotropic glutamate receptors. Physical Chemistry Chemical Physics 12:14057-14066. PMID: 20856958. DOI: 10.1039/C004336B
  72. Vijayan R., Iorga B., and Biggin P.C. (2010) Chapter: Computational approaches to ionotropic glutamate receptors in Molecular Simulations and Biomembranes: From Biophysics to Function RSC Publishing. ISBN: 978-0-85404-189-3. (Also cover image).
  73. Vijayan R., and Biggin P.C. (2010) Conformational preferences of a 14-residue fibrillogenic peptide from acetylcholinesterase. Biochemistry 49:3678-3684. PMID: 20356043. DOI: 10.1021/bi1001807
  74. Vijayan R., Plested A.J.R., Mayer M.L., and Biggin P.C. (2009) Selectivity and cooperativity of modulatory ions in a neurotransmitter receptor. Biophysical Journal. 96:1751-1760. PMID: 19254535. DOI: 10.1016/j.bpj.2008.11.039
  75. Chew C., Vijayan R., Chang J., Zitzmann N., and Biggin P.C. (2009) Determination of pore-lining residues in the Hepatitis C virus p7 protein. Biophysical Journal 96:L10-L12. PMID: 19167280. DOI: 10.1016/j.bpj.2008.10.004
  76. Vijayan R., and Biggin P.C. (2008) A steroid in a lipid bilayer: Localization, orientation and energetics. Biophysical Journal 95:L45-L47. PMID: 18689457. DOI: 10.1529/biophysj.108.140087
  77. Plested A.J.R.*, Vijayan R.*, Biggin P.C., and Mayer M.L. (2008) Molecular basis of kainate receptor modulation by sodium. Neuron 58:720-735. PMID: 18549784. DOI: 10.1016/j.neuron.2008.04.001 (* - Joint first author)
  78. Moroni M., Vijayan R., Carbone A., Zwart R., Biggin P.C., and Bermudez I. (2008) Non-agonist binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the α4β2 nicotinic receptor: an α4-α4 interface is required for Zn2+ potentiation. Journal of Neuroscience 28:6884-6894. PMID: 18596163. DOI: 10.1523/jneurosci.1228-08.2008
  79. Amiri S., Shimomura M., Vijayan R., Nishiwaki H., Akamatsu M., Matsuda K., Jones A.K., Sansom M.S.P., Biggin P.C., and Sattelle D.B. (2008) A role for Leu118 of loop E in agonist binding to the α7 nicotinic acetylcholine receptor. Molecular Pharmacology 73:1659-1667. PMID: 18339894. DOI:10.1124/mol.107.041590