PDB code: 1AP9_A
Observed 10-30; 39-62; 77-101; 105-127; 134-157; 169-191; 202-224; 
TMHindex 10-31; 41-62; 81-100; 106-127; 134-156; 176-191; 199-226; 
MEMBRAIN 10-29; 43-63; 78-97; 107-127; 134-154; 172-191; 203-224; 
THUMBU 16-27; 49-65; 85-106; 126-155; 179-194; 202-217; 
SOSUI 11-33; 46-68; 78-100; 107-129; 137-159; 177-199; 204-225; 
DAS_TMfilter 14-28; 47-67; 88-101; 110-123; 139-156; 178-190; 203-223; 
TOP_PRED 9-29; 44-64; 83-103; 106-126; 138-158; 176-196; 204-224; 
TMHMM_2.0 10-29; 42-64; 79-101; 108-130; 135-157; 177-199; 
Phobius 12-29; 41-63; 83-101; 108-129; 135-156; 177-199; 205-224; 

PDB code: 1AR1_A
Observed 27-59; 84-121; 130-151; 178-206; 218-251; 263-298; 304-322; 334-362; 370-395; 404-430; 441-468; 483-513; 
TMHindex 32-51; 88-125; 127-151; 179-206; 213-249; 263-296; 303-325; 338-363; 372-392; 408-433; 445-466; 483-515; 
MEMBRAIN 28-55; 86-118; 129-151; 177-205; 217-248; 264-294; 305-324; 334-361; 370-392; 406-435; 442-467; 482-512; 
THUMBU 36-51; 89-113; 133-146; 185-200; 216-244; 272-290; 308-327; 346-356; 371-390; 409-429; 449-459; 491-511; 
SOSUI 32-53; 90-112; 133-155; 181-203; 221-243; 276-298; 304-326; 339-361; 374-396; 408-430; 441-463; 492-514; 
DAS_TMfilter 32-52; 90-112; 137-150; 182-204; 215-246; 272-294; 303-325; 341-357; 373-392; 409-430; 450-460; 492-513; 
TOP_PRED 31-51; 93-113; 134-154; 157-177; 181-201; 217-237; 278-298; 305-325; 337-357; 372-392; 413-433; 446-466; 493-513; 
TMHMM_2.0 31-53; 90-112; 132-154; 183-205; 225-247; 272-294; 301-323; 338-360; 373-395; 410-432; 445-467; 491-513; 
Phobius 31-53; 91-115; 135-154; 181-207; 219-246; 266-290; 302-326; 338-361; 373-392; 412-432; 444-465; 491-512; 

PDB code: 1AT9_A
Observed 9-31; 37-62; 80-100; 106-126; 131-155; 165-191; 201-224; 
TMHindex 8-33; 42-63; 80-101; 108-127; 131-157; 170-190; 201-226; 
MEMBRAIN 10-30; 43-63; 78-97; 107-127; 134-154; 172-191; 203-224; 
THUMBU 16-27; 49-65; 85-106; 126-155; 179-194; 202-217; 
SOSUI 10-32; 45-67; 77-99; 106-128; 136-158; 176-198; 203-224; 
DAS_TMfilter 14-28; 46-67; 88-101; 109-124; 138-156; 178-190; 203-223; 
TOP_PRED 8-28; 43-63; 82-102; 105-125; 137-157; 175-195; 203-223; 
TMHMM_2.0 10-29; 42-64; 79-101; 108-130; 135-157; 177-199; 
Phobius 12-29; 41-63; 83-101; 108-129; 135-156; 177-199; 205-224; 

PDB code: 1BCC_C
Observed 33-54; 76-106; 112-135; 172-204; 221-245; 289-309; 321-340; 346-379; 
TMHindex 33-54; 76-105; 116-135; 177-202; 232-245; 287-309; 320-341; 347-375; 
MEMBRAIN 33-54; 88-102; 114-134; 142-152; 179-200; 228-248; 291-307; 321-338; 351-372; 
THUMBU 33-51; 83-102; 121-139; 147-160; 180-197; 233-244; 293-303; 324-337; 353-366; 
SOSUI 33-55; 82-104; 114-136; 140-162; 179-201; 230-252; 280-302; 321-343; 349-371; 
DAS_TMfilter 36-55; 89-101; 117-133; 179-199; 231-247; 291-308; 324-339; 354-370; 
TOP_PRED 34-54; 82-102; 116-136; 150-170; 179-199; 230-250; 289-309; 321-341; 353-373; 
TMHMM_2.0 34-56; 83-105; 117-139; 144-166; 179-201; 230-252; 289-308; 323-341; 348-370; 
Phobius 31-53; 88-108; 114-134; 141-159; 179-201; 230-251; 289-309; 321-341; 347-367; 

PDB code: 1EHK_A
Observed 17-48; 65-97; 103-125; 143-173; 180-212; 220-254; 262-283; 292-326; 344-366; 380-409; 415-444; 461-493; 527-550; 
TMHindex 20-46; 66-93; 103-127; 144-168; 179-211; 221-253; 262-281; 295-322; 346-360; 385-407; 420-446; 466-493; 526-551; 
MEMBRAIN 19-48; 66-96; 103-127; 142-169; 177-210; 221-252; 262-285; 292-325; 329-337; 344-365; 379-408; 419-444; 461-492; 529-545
THUMBU 24-40; 74-88; 105-128; 147-163; 182-216; 228-247; 265-279; 301-315; 352-360; 392-401; 421-445; 467-489; 526-547; 
SOSUI 21-43; 71-93; 109-131; 145-167; 189-211; 233-255; 262-284; 299-321; 341-363; 385-407; 421-443; 467-489; 527-549; 
DAS_TMfilter 21-39; 72-88; 108-126; 145-164; 181-216; 234-249; 265-279; 298-316; 347-359; 389-403; 422-441; 466-493; 527-547; 
TOP_PRED 21-41; 74-94; 103-123; 144-164; 182-202; 232-252; 264-284; 299-319; 345-365; 387-407; 420-440; 473-493; 527-547; 
TMHMM_2.0 21-43; 70-92; 105-127; 142-164; 187-209; 229-251; 264-286; 301-323; 343-365; 385-407; 420-442; 471-493; 527-549; 
Phobius 21-44; 64-92; 104-125; 145-164; 184-207; 227-251; 263-281; 301-324; 345-365; 385-408; 420-443; 463-489; 527-551; 

PDB code: 1EYS_L
Observed 32-56; 91-118; 123-141; 178-206; 233-258; 
TMHindex 31-54; 91-109; 123-141; 183-197; 233-258; 
MEMBRAIN 30-56; 90-118; 122-146; 177-202; 233-260; 
THUMBU 22-53; 96-108; 127-151; 177-198; 231-259; 
SOSUI 12-34; 36-58; 93-115; 124-146; 235-257; 
DAS_TMfilter 24-54; 97-105; 123-148; 183-200; 232-259; 
TOP_PRED 31-51; 91-111; 122-142; 179-199; 240-260; 
TMHMM_2.0 29-51; 91-110; 123-145; 183-205; 240-262; 
Phobius 21-51; 92-110; 122-142; 182-205; 240-263; 

PDB code: 1EYS_M
Observed 53-77; 111-138; 143-161; 198-225; 262-285; 
TMHindex 53-75; 110-134; 138-161; 202-222; 271-287; 
MEMBRAIN 52-76; 110-138; 142-166; 197-223; 266-288; 
THUMBU 53-79; 114-128; 145-167; 199-222; 264-292; 
SOSUI 51-73; 110-132; 145-167; 202-224; 268-290; 
DAS_TMfilter 50-76; 113-129; 147-165; 202-222; 271-289; 
TOP_PRED 52-72; 110-130; 143-163; 200-220; 268-288; 
TMHMM_2.0 50-72; 111-133; 145-167; 203-225; 267-289; 
Phobius 50-76; 113-133; 145-166; 200-223; 267-290; 

PDB code: 1EYS_H
Observed 10-34; 
TMHindex 14-28; 
MEMBRAIN 11-29; 
THUMBU 10-26; 
SOSUI 9-30; 
DAS_TMfilter 16-27; 
TOP_PRED 11-31; 83-103; 
TMHMM_2.0 13-30; 
Phobius 12-30; 

PDB code: 1FX8_A
Observed 6-35; 40-64; 68-79; 85-109; 144-168; 178-199; 203-217; 233-255; 
TMHindex 4-35; 40-64; 69-79; 88-110; 144-168; 178-199; 212-222; 232-253; 
MEMBRAIN 10-31; 40-62; 68-78; 84-108; 146-165; 178-198; 211-219; 232-254; 
THUMBU 15-33; 43-74; 94-110; 149-164; 180-195; 236-247; 
SOSUI 15-37; 43-65; 86-108; 145-167; 178-200; 230-251; 
DAS_TMfilter 15-32; 46-61; 70-79; 94-110; 150-166; 178-194; 233-249; 
TOP_PRED 12-32; 44-64; 86-106; 148-168; 177-197; 230-250; 
TMHMM_2.0 12-34; 44-66; 87-109; 143-165; 178-200; 229-251; 
Phobius 12-34; 46-79; 86-108; 145-166; 178-202; 230-251; 

PDB code: 1IH5_A
Observed 10-34; 47-64; 77-88; 96-112; 140-159; 169-184; 189-202; 210-229; 
TMHindex 11-37; 51-63; 77-89; 96-113; 140-156; 166-184; 189-205; 207-233; 
MEMBRAIN 12-35; 48-69; 76-87; 91-117; 138-156; 166-187; 209-230; 
THUMBU 16-32; 82-112; 173-183; 213-227; 
SOSUI 13-35; 87-109; 134-155; 167-189; 205-227; 
DAS_TMfilter 15-33; 78-115; 78-115; 143-153; 170-184; 214-231; 
TOP_PRED 15-35; 52-72; 75-95; 101-121; 138-158; 164-184; 207-227; 
TMHMM_2.0 13-35; 65-87; 94-116; 136-155; 167-189; 209-231; 
Phobius 9-33; 53-73; 94-119; 139-157; 164-184; 210-231; 

PDB code: 1IWG_A
Observed 9-28; 335-360; 365-385; 392-413; 440-460; 472-495; 541-560; 863-888; 894-916; 927-949; 976-996; 1011-1029; 
TMHindex 12-27; 333-360; 366-390; 387-412; 440-461; 472-495; 541-558; 876-892; 898-918; 928-946; 976-994; 1006-1028; 
MEMBRAIN 9-28; 341-361; 364-387; 391-410; 438-464; 466-495; 538-560; 873-893; 895-922; 923-943; 971-992; 1001-1029; 
THUMBU 10-27; 341-359; 390-408; 443-459; 471-492; 538-557; 877-914; 974-991; 1010-1026; 
SOSUI 9-31; 335-357; 367-389; 396-418; 441-463; 475-497; 541-563; 872-894; 897-919; 973-995; 1007-1029; 
DAS_TMfilter 10-29; 342-362; 365-410; 365-410; 442-459; 472-494; 540-558; 876-917; 876-917; 975-992; 1010-1029; 
TOP_PRED 9-29; 32-52; 131-151; 342-362; 370-390; 441-461; 470-490; 541-561; 660-680; 872-892; 898-918; 926-946; 974-994; 1009-1029; 
TMHMM_2.0 10-32; 340-359; 369-391; 438-460; 470-492; 542-564; 873-892; 899-921; 926-948; 975-997; 1007-1029; 
Phobius 12-32; 340-359; 366-390; 396-416; 437-458; 470-493; 541-557; 875-892; 899-919; 925-946; 975-995; 1007-1029; 

PDB code: 1JGJ_A
Observed 1-27; 33-56; 70-92; 94-118; 121-150; 153-181; 189-216; 
TMHindex 1-28; 43-58; 74-87; 89-116; 123-148; 155-184; 186-217; 
MEMBRAIN 6-25; 36-60; 70-88; 97-119; 122-144; 161-181; 190-211; 
THUMBU 10-22; 43-62; 75-95; 104-113; 122-141; 164-183; 185-208; 
SOSUI 4-26; 39-61; 74-95; 98-120; 126-148; 156-178; 189-211; 
DAS_TMfilter 8-20; 41-58; 77-92; 101-114; 128-142; 167-182; 184-206; 
TOP_PRED 4-24; 38-58; 74-94; 98-118; 124-144; 165-185; 193-213; 
TMHMM_2.0 4-26; 39-61; 76-93; 98-120; 124-146; 167-189; 194-213; 
Phobius 6-25; 37-61; 73-91; 98-118; 124-142; 163-182; 194-213; 

PDB code: 1KQG_B
Observed 256-280; 
TMHindex 257-278; 
MEMBRAIN 257-275; 
THUMBU 264-274; 
SOSUI 258-280; 
DAS_TMfilter 262-275; 
TOP_PRED 130-150; 259-279; 
TMHMM_2.0 260-279; 
Phobius 260-279; 

PDB code: 1KQG_C
Observed 11-37; 49-76; 110-135; 144-176; 
TMHindex 13-37; 49-76; 110-137; 150-174; 
MEMBRAIN 17-40; 57-75; 115-136; 146-177; 
THUMBU 15-38; 56-74; 118-141; 151-176; 
SOSUI 18-40; 55-77; 115-137; 150-172; 
DAS_TMfilter 18-39; 56-76; 117-137; 149-175; 
TOP_PRED 20-40; 55-75; 115-135; 156-176; 
TMHMM_2.0 21-40; 55-77; 117-139; 154-176; 
Phobius 21-43; 55-76; 117-138; 150-174; 

PDB code: 1L7V_A
Observed 2-32; 47-81; 93-107; 114-138; 142-166; 191-206; 229-249; 258-267; 272-296; 305-324; 
TMHindex 10-36; 50-86; 88-107; 115-135; 142-166; 192-204; 225-253; 254-268; 273-300; 301-324; 
MEMBRAIN 14-34; 55-77; 94-111; 114-136; 144-164; 191-208; 231-256; 274-295; 300-320; 
THUMBU 18-32; 57-74; 118-134; 147-164; 192-207; 232-267; 280-305; 307-317; 
SOSUI 13-34; 52-74; 102-124; 141-163; 184-200; 228-250; 265-287; 292-314; 
DAS_TMfilter 16-33; 59-74; 97-107; 117-135; 145-163; 193-204; 242-266; 279-319; 279-319; 
TOP_PRED 12-32; 58-78; 85-105; 110-130; 142-162; 181-201; 230-250; 263-283; 292-312; 
TMHMM_2.0 13-35; 55-77; 89-111; 115-137; 144-166; 239-261; 274-296; 300-322; 
Phobius 58-77; 89-109; 115-133; 145-168; 188-206; 213-231; 243-263; 275-297; 303-322; 

PDB code: 1LGH_A
Observed 15-39; 
TMHindex 15-39; 
MEMBRAIN 15-38; 
THUMBU 15-42; 
SOSUI 9-31; 34-56; 
DAS_TMfilter 16-43; 
TOP_PRED 16-36; 
TMHMM_2.0 21-43; 
Phobius 20-48; 

PDB code: 1LGH_B
Observed 10-41; 
TMHindex 9-41; 
MEMBRAIN 20-39; 
THUMBU 27-36; 
SOSUI 20-42; 
DAS_TMfilter 26-41; 
TOP_PRED 22-42; 
TMHMM_2.0 22-41; 
Phobius 20-41; 

PDB code: 1NEK_C
Observed 21-54; 67-97; 102-129; 
TMHindex 23-54; 67-97; 102-129; 
MEMBRAIN 27-59; 63-99; 109-123; 
THUMBU 26-49; 66-91; 
SOSUI 25-47; 65-87; 109-129; 
DAS_TMfilter 26-50; 68-88; 113-125; 
TOP_PRED 32-52; 62-82; 109-129; 
TMHMM_2.0 27-49; 64-86; 112-128; 
Phobius 20-48; 68-89; 110-128; 

PDB code: 1NEK_D
Observed 11-38; 54-84; 86-114; 
TMHindex 14-38 ; 53-81 ; 89-115; 
MEMBRAIN 19-40; 49-78; 91-109; 
THUMBU 19-45; 51-80; 88-106; 
SOSUI 16-38; 51-73; 89-111; 
DAS_TMfilter 18-37; 54-74; 88-111; 
TOP_PRED 21-41; 59-79; 95-115; 
TMHMM_2.0 16-38; 48-70; 91-113; 
Phobius 17-39; 59-80; 92-113; 

PDB code: 1NKZ_A
Observed 11-36; 
TMHindex 11-36; 
TMHindex 11-36; 
MEMBRAIN 13-35; 
THUMBU 15-40; 
SOSUI 11-33; 
DAS_TMfilter 13-38; 
TOP_PRED 12-32; 
TMHMM_2.0 13-35; 
Phobius 14-35; 

PDB code: 1OCC_D
Observed 77-103; 
TMHindex 78-99; 
MEMBRAIN 77-101; 
THUMBU 85-98; 
SOSUI 79-101; 
DAS_TMfilter 84-97; 
TOP_PRED 79-99; 
TMHMM_2.0 81-98; 
Phobius 80-98; 

PDB code: 1OCC_G
Observed 13-37; 
TMHindex 13-37; 
MEMBRAIN 14-36; 
THUMBU 21-32; 
SOSUI 16-37; 
DAS_TMfilter 21-30; 
TOP_PRED 18-38; 
TMHMM_2.0 15-37; 
Phobius 16-37; 

PDB code: 1OCC_J
Observed 26-54; 
TMHindex 26-54; 
MEMBRAIN 26-52; 
THUMBU 38-48; 
SOSUI 33-54; 
DAS_TMfilter 35-48; 
TOP_PRED 34-54; 
TMHMM_2.0 30-52; 
Phobius 30-53; 

PDB code: 1OCC_K
Observed 9-35; 
TMHindex 9-35; 
MEMBRAIN 10-34; 
THUMBU 21-34; 
SOSUI 14-36; 
DAS_TMfilter 18-34; 
TOP_PRED 14-34; 
TMHMM_2.0 13-35; 
Phobius 12-32; 

PDB code: 1OCC_L
Observed 18-44; 
TMHindex 19-44; 
MEMBRAIN 18-41; 
THUMBU 26-36; 
SOSUI 20-42; 
DAS_TMfilter 24-35; 
TOP_PRED 20-40; 
TMHMM_2.0 20-42; 
Phobius 20-40; 

PDB code: 1OCC_M
Observed 12-35; 
TMHindex 12-35; 
MEMBRAIN 12-34; 
THUMBU 23-32; 
SOSUI 15-37; 
DAS_TMfilter 19-34; 
TOP_PRED 15-35; 
TMHMM_2.0 15-37; 
Phobius 16-35; 

PDB code: 1OED_A
Observed 2-29; 32-61; 65-92; 194-227; 
TMHindex 2-28; 32-60; 66-89; 193-222; 
MEMBRAIN 6-24; 35-50; 61-87; 194-219; 
THUMBU 10-22; 39-56; 65-84; 194-216; 
SOSUI 3-25; 35-57; 64-86; 196-218; 
DAS_TMfilter 6-25; 35-57; 63-86; 194-217; 
TOP_PRED 7-27; 33-53; 67-87; 198-218; 
TMHMM_2.0 4-26; 35-57; 67-89; 199-221; 
Phobius 6-25; 37-55; 67-86; 199-221; 

PDB code: 1OED_B
Observed 2-29; 32-61; 67-91; 216-246; 
TMHindex 1-27; 34-59; 66-91; 215-243; 
MEMBRAIN 6-25; 35-50; 61-87; 217-241; 
THUMBU 10-22; 38-50; 63-84; 219-238; 
SOSUI 3-25; 32-54; 63-85; 218-240; 
DAS_TMfilter 6-26; 36-52; 60-87; 218-238; 
TOP_PRED 5-25; 32-52; 67-87; 222-242; 
TMHMM_2.0 4-26; 33-51; 66-88; 222-240; 
Phobius 6-26; 33-51; 63-88; 222-240; 

PDB code: 1OED_C
Observed 2-29; 32-61; 65-92; 228-260; 
TMHindex 1-27; 34-52; 60-92; 227-253; 
MEMBRAIN 6-24; 35-50; 61-87; 227-252; 
THUMBU 10-22; 65-84; 233-250; 
SOSUI 4-26; 32-54; 64-86; 231-253; 
DAS_TMfilter 8-24; 37-50; 61-86; 233-251; 
TOP_PRED 7-27; 32-52; 67-87; 232-252; 
TMHMM_2.0 5-27; 34-53; 68-90; 232-254; 
Phobius 6-25; 37-55; 67-88; 232-254; 

PDB code: 1OED_E
Observed 3-28; 32-62; 67-93; 227-260; 
TMHindex 1-27; 33-67; 62-93; 232-260; 
MEMBRAIN 6-25; 36-51; 62-88; 227-251; 
THUMBU 10-23; 66-87; 229-249; 
SOSUI 4-26; 35-57; 67-89; 229-251; 
DAS_TMfilter 7-26; 38-52; 64-89; 232-251; 
TOP_PRED 7-27; 33-53; 68-88; 232-252; 
TMHMM_2.0 5-27; 34-53; 68-90; 232-254; 
Phobius 6-24; 36-56; 68-91; 232-254; 

PDB code: 1OKC_A
Observed 8-27; 66-89; 108-136; 169-197; 206-230; 266-290; 
TMHindex 8-27; 67-87; 108-136; 172-195; 207-229; 270-291; 
MEMBRAIN 10-29; 70-89; 112-134; 173-193; 211-230; 270-290; 
THUMBU 214-222; 
SOSUI 
DAS_TMfilter 
TOP_PRED 9-29; 113-133; 207-227; 
TMHMM_2.0 111-133; 171-193; 208-230; 
Phobius 171-189; 209-230; 

PDB code: 1PRC_M
Observed 52-76; 111-137; 143-166; 198-223; 260-284; 
TMHindex 54-72; 111-138; 142-163; 200-223; 269-285; 
MEMBRAIN 50-76; 110-137; 141-165; 196-222; 265-287; 
THUMBU 52-77; 109-127; 143-164; 200-221; 265-292; 
SOSUI 52-74; 108-130; 141-163; 202-224; 267-289; 
DAS_TMfilter 51-74; 114-125; 144-164; 204-222; 269-288; 
TOP_PRED 54-74; 109-129; 144-164; 199-219; 266-286; 
TMHMM_2.0 49-71; 110-132; 144-166; 203-225; 267-289; 
Phobius 49-75; 112-132; 144-165; 202-225; 266-289; 

PDB code: 1PSS_L
Observed 32-55; 83-111; 116-138; 171-198; 225-250; 
TMHindex 28-47; 83-111; 116-140; 171-191; 225-248; 
MEMBRAIN 27-51; 78-106; 110-134; 165-192; 221-249; 
THUMBU 18-53; 85-95; 112-146; 172-187; 223-254; 
SOSUI 24-46; 78-100; 111-133; 170-192; 225-247; 
DAS_TMfilter 19-50; 85-93; 111-136; 171-191; 220-249; 
TOP_PRED 27-47; 79-99; 110-130; 168-188; 229-249; 
TMHMM_2.0 25-47; 79-101; 108-130; 171-193; 230-252; 
Phobius 21-47; 80-98; 110-130; 170-194; 228-252; 

PDB code: 1PSS_M
Observed 54-78; 109-139; 147-168; 200-226; 262-286; 
TMHindex 52-76; 109-136; 147-164; 198-218; 262-286; 
MEMBRAIN 41-71; 108-134; 138-162; 193-219; 262-284; 
THUMBU 41-80; 107-128; 142-163; 193-218; 260-286; 
SOSUI 47-69; 106-127; 141-163; 200-222; 267-289; 
DAS_TMfilter 45-69; 109-122; 144-162; 198-219; 265-284; 
TOP_PRED 25-45; 50-70; 106-126; 140-160; 196-216; 263-283; 
TMHMM_2.0 49-71; 107-129; 141-163; 199-221; 263-285; 
Phobius 45-71; 108-130; 142-162; 199-221; 263-286; 

PDB code: 1PV7_A
Observed 6-39; 41-59; 74-101; 103-137; 139-165; 165-186; 220-248; 253-277; 287-308; 311-341; 357-377; 377-400; 
TMHindex 5-35; 37-59; 77-98; 116-132; 136-165; 165-187; 219-248; 253-282; 282-306; 313-346; 352-377; 377-405;
MEMBRAIN 8-33; 45-64; 74-100; 102-125; 141-163; 167-187; 211-241; 256-281; 290-307; 312-335; 349-372; 379-399; 
THUMBU 10-32; 49-59; 77-95; 103-121; 149-187; 268-279; 320-330; 345-365; 379-397; 
SOSUI 11-33; 44-66; 75-97; 106-128; 144-166; 174-196; 215-237; 260-282; 288-310; 313-335; 346-368; 379-401; 
DAS_TMfilter 11-30; 48-64; 76-116; 76-116; 153-162; 171-187; 224-232; 294-302; 320-332; 348-367; 381-400; 
TOP_PRED 7-27; 45-65; 78-98; 102-122; 167-187; 219-239; 263-283; 291-311; 315-335; 349-369; 382-402; 
TMHMM_2.0 13-35; 45-67; 76-98; 103-125; 145-164; 168-187; 222-239; 261-283; 304-326; 346-368; 380-402; 
Phobius 12-34; 46-66; 75-95; 101-122; 143-162; 168-187; 222-239; 259-279; 291-310; 316-337; 349-369; 381-401; 

PDB code: 1PW4_A
Observed 19-58; 63-89; 93-113; 120-148; 152-181; 189-208; 252-283; 287-317; 321-342; 346-375; 379-410; 414-449; 
TMHindex 14-56; 63-87; 91-115; 118-149; 152-184; 188-209; 252-283; 288-316; 322-341; 347-374; 380-409; 415-436; 
MEMBRAIN 26-53; 62-84; 93-114; 116-144; 156-182; 185-206; 253-279; 286-313; 320-344; 346-371; 381-408; 412-434; 
THUMBU 30-46; 98-133; 165-207; 251-271; 327-337; 345-368; 388-406; 415-433; 
SOSUI 26-43; 102-124; 160-181; 187-208; 251-273; 290-312; 320-342; 350-372; 384-406; 414-435; 
DAS_TMfilter 29-42; 68-77; 94-132; 170-181; 189-206; 252-271; 324-338; 349-371; 387-406; 415-436; 
TOP_PRED 25-45; 66-86; 94-114; 163-183; 187-207; 252-272; 292-312; 321-341; 350-370; 384-404; 415-435; 
TMHMM_2.0 27-44; 64-86; 93-115; 119-141; 154-176; 186-205; 253-272; 292-311; 318-340; 350-372; 385-407; 417-436; 
Phobius 25-43; 63-81; 93-112; 118-137; 158-182; 188-207; 253-271; 291-310; 322-341; 347-372; 384-404; 416-436; 

PDB code: 1Q90_D
Observed 38-58; 93-109; 126-147; 
TMHindex 38-58; 93-109; 130-146; 
MEMBRAIN 34-57; 95-113; 128-146; 
THUMBU 39-54; 88-109; 132-150; 
SOSUI 36-58; 89-111; 131-153; 
DAS_TMfilter 38-55; 94-110; 129-147; 
TOP_PRED 37-57; 94-114; 127-147; 
TMHMM_2.0 36-58; 95-117; 129-151; 
Phobius 36-57; 95-114; 126-145; 

PDB code: 1QHJ_A
Observed 6-32; 37-58; 80-100; 105-127; 131-160; 165-191; 201-224; 
TMHindex 6-33; 42-53; 80-103; 105-127; 132-160; 165-196; 196-226; 
MEMBRAIN 10-29; 43-63; 78-97; 107-127; 134-154; 172-191; 203-224; 
THUMBU 16-27; 49-65; 85-106; 126-155; 179-194; 202-217; 
SOSUI 11-33; 46-68; 78-100; 107-129; 137-159; 177-199; 204-225; 
DAS_TMfilter 14-28; 47-67; 88-101; 109-124; 138-156; 178-190; 203-223; 
TOP_PRED 9-29; 44-64; 83-103; 106-126; 138-158; 176-196; 204-224; 
TMHMM_2.0 10-29; 42-64; 79-101; 108-130; 135-157; 177-199; 
Phobius 12-29; 41-63; 83-101; 108-129; 135-156; 177-199; 205-224; 

PDB code: 1QLB_C
Observed 22-52; 77-100; 121-149; 169-194; 202-237; 
TMHindex 24-52; 80-100; 125-149; 165-199; 210-237; 
MEMBRAIN 32-55; 78-95; 128-145; 166-181; 214-229; 
THUMBU 33-54; 76-96; 129-146; 166-185; 218-228; 
SOSUI 33-55; 77-98; 129-151; 171-193; 213-232; 
DAS_TMfilter 33-57; 76-97; 131-147; 167-186; 214-231; 
TOP_PRED 32-52; 76-96; 123-143; 163-183; 212-232; 
TMHMM_2.0 31-53; 76-98; 125-147; 167-189; 215-232; 
Phobius 28-53; 77-98; 125-147; 167-191; 212-232; 

PDB code: 1RC2_B
Observed 3-26; 34-54; 63-73; 79-104; 130-154; 161-182; 186-198; 206-225; 
TMHindex 7-29; 31-53; 64-74; 81-104; 129-156; 159-183; 186-201; 203-226; 
MEMBRAIN 6-24; 35-57; 64-73; 79-104; 132-151; 161-182; 204-224; 
THUMBU 13-25; 28-54; 87-103; 134-145; 164-177; 199-219; 
SOSUI 5-27; 35-57; 81-103; 131-153; 161-183; 205-227; 
DAS_TMfilter 13-26; 32-55; 85-103; 132-150; 162-179; 206-221; 
TOP_PRED 9-29; 35-55; 85-105; 130-150; 156-176; 203-223; 
TMHMM_2.0 7-29; 33-55; 81-103; 127-149; 156-178; 205-227; 
Phobius 36-60; 81-103; 129-149; 161-180; 206-226; 

PDB code: 1RHZ_A
Observed 22-41; 59-89; 105-129; 136-161; 168-188; 206-229; 255-276; 312-333; 375-396; 400-415; 
TMHindex 33-41; 65-94; 105-129; 136-161; 168-185; 208-223; 256-274; 312-333; 381-401; 395-410; 
MEMBRAIN 26-44; 56-66; 71-90; 111-132; 136-159; 167-192; 205-227; 253-282; 313-336; 375-396; 398-413; 
THUMBU 34-50; 74-92; 114-132; 140-158; 173-181; 209-229; 256-280; 312-333; 381-407; 
SOSUI 31-53; 71-93; 110-132; 138-160; 167-189; 208-230; 258-280; 313-335; 384-406; 
DAS_TMfilter 31-44; 69-90; 115-157; 115-157; 170-179; 211-226; 255-271; 314-333; 381-410; 
TOP_PRED 27-47; 67-87; 125-145; 168-188; 209-229; 257-277; 292-312; 315-335; 374-394; 
TMHMM_2.0 33-55; 70-92; 113-135; 139-157; 164-186; 209-231; 252-274; 313-335; 383-405; 
Phobius 29-47; 67-93; 113-132; 138-157; 169-189; 209-226; 247-269; 316-335; 373-391; 397-415; 

PDB code: 1RWT_A
Observed 55-87; 124-144; 170-201; 
TMHindex 55-83; 123-144; 187-200; 
MEMBRAIN 56-87; 122-141; 179-198; 
THUMBU 124-137; 
SOSUI 118-140; 
DAS_TMfilter 
TOP_PRED 66-86; 120-140; 184-204; 
TMHMM_2.0
Phobius

PDB code: 1SOR_A
Observed 5-32; 40-63; 68-78; 82-108; 126-150; 159-180; 184-194; 200-222; 
TMHindex 4-35; 37-62; 68-78; 80-102; 126-144; 154-178; 183-191; 201-222; 
MEMBRAIN 8-29; 35-57; 64-75; 77-106; 125-144; 154-175; 197-219; 
THUMBU 10-29; 37-55; 74-96; 129-140; 160-171; 202-214; 
SOSUI 5-27; 35-57; 75-97; 122-143; 154-174; 193-215; 
DAS_TMfilter 11-26; 37-54; 78-101; 128-142; 157-170; 205-218; 
TOP_PRED 8-28; 36-56; 82-102; 126-146; 153-173; 197-217; 
TMHMM_2.0 5-27; 37-59; 79-101; 121-143; 156-178; 198-220; 
Phobius 9-31; 37-58; 79-103; 123-144; 156-175; 198-220; 

PDB code: 1U7G_A
Observed 6-34; 37-69; 96-120; 124-149; 163-182; 194-221; 224-254; 257-273; 280-307; 310-333; 347-381; 
TMHindex 11-39; 47-63; 100-119; 125-150; 164-182; 196-219; 226-252; 259-275; 278-307; 313-338; 342-385; 
MEMBRAIN 12-34; 45-68; 97-118; 125-149; 165-181; 199-216; 225-249; 260-275; 277-301; 317-337; 347-379; 
THUMBU 17-29; 48-66; 99-117; 129-147; 165-180; 204-215; 231-254; 266-299; 319-335; 355-374; 
SOSUI 11-33; 41-63; 111-133; 155-176; 187-209; 217-239; 245-267; 270-292; 307-329; 347-369; 
DAS_TMfilter 16-32; 48-64; 107-119; 124-144; 169-180; 230-247; 262-271; 277-297; 321-333; 359-373; 
TOP_PRED 11-31; 41-61; 94-114; 119-139; 154-174; 190-210; 219-239; 246-266; 273-293; 310-330; 345-365; 
TMHMM_2.0 10-32; 41-63; 98-120; 127-149; 164-183; 196-215; 225-247; 254-276; 280-302; 315-337; 352-374; 
Phobius 12-32; 44-64; 98-120; 127-149; 161-183; 195-214; 226-247; 254-272; 278-302; 314-338; 358-377; 

PDB code: 1UAZ_A
Observed 15-38; 44-69; 86-106; 110-133; 136-160; 170-198; 206-231; 
TMHindex 20-38; 50-70; 84-105; 111-131; 138-161; 178-197; 204-219; 
MEMBRAIN 17-36; 49-71; 85-104; 112-134; 139-161; 178-198; 209-230; 
THUMBU 22-34; 55-70; 90-103; 118-132; 141-159; 179-197; 205-223; 
SOSUI 17-39; 50-72; 89-111; 113-135; 142-164; 177-199; 210-231; 
DAS_TMfilter 19-35; 54-70; 94-107; 117-132; 144-161; 179-197; 205-229; 
TOP_PRED 16-36; 53-73; 89-109; 114-134; 142-162; 179-199; 210-230; 
TMHMM_2.0 15-35; 48-70; 85-107; 114-133; 143-162; 175-197; 207-229; 
Phobius 17-35; 47-69; 89-107; 114-135; 141-159; 180-198; 204-230; 

PDB code: 1VF5_C
Observed 251-280; 
TMHindex 259-270; 
MEMBRAIN 255-271; 
THUMBU 256-270; 
SOSUI 
DAS_TMfilter 260-270; 
TOP_PRED 255-275; 
TMHMM_2.0 257-274; 
Phobius 257-274; 

PDB code: 1VF5_D
Observed 18-43; 
TMHindex 20-38; 
MEMBRAIN 19-41; 
THUMBU 25-36; 
SOSUI 
DAS_TMfilter 24-37; 
TOP_PRED 18-38; 101-121; 
TMHMM_2.0 21-43; 
Phobius 21-39; 

PDB code: 1VGO_A
Observed 13-36; 40-66; 85-107; 109-132; 135-159; 169-196; 205-230; 
TMHindex 14-41; 51-66; 81-104; 112-130; 137-161; 178-196; 202-218; 
MEMBRAIN 15-34; 47-68; 84-102; 111-133; 138-159; 177-197; 207-229; 
THUMBU 20-32; 52-72; 88-102; 116-126; 143-159; 181-204; 
SOSUI 12-34; 55-77; 88-110; 112-134; 141-163; 175-197; 209-230; 
DAS_TMfilter 17-32; 51-69; 92-106; 114-130; 143-160; 179-196; 206-228; 
TOP_PRED 13-33; 51-71; 88-108; 112-132; 140-160; 178-198; 209-229; 
TMHMM_2.0 15-33; 46-68; 83-105; 110-132; 142-161; 174-196; 206-228; 
Phobius 15-33; 45-68; 88-106; 113-134; 140-158; 179-197; 203-229; 

PDB code: 1XIO_A
Observed 2-27; 33-57; 69-92; 98-122; 124-148; 158-186; 194-224; 
TMHindex 1-26; 33-58; 64-92; 98-119; 127-152; 158-189; 191-218; 
MEMBRAIN 6-25; 36-58; 69-89; 99-122; 127-149; 166-186; 196-219; 
THUMBU 40-50; 75-87; 130-146; 168-186; 196-212; 
SOSUI 4-26; 33-55; 74-95; 101-123; 127-149; 169-191; 
DAS_TMfilter 39-50; 78-89; 103-116; 131-146; 169-185; 199-212; 
TOP_PRED 5-25; 37-57; 75-95; 99-119; 129-149; 168-188; 196-216; 
TMHMM_2.0 5-24; 37-56; 76-95; 100-119; 129-147; 168-187; 197-216; 
Phobius 6-25; 37-56; 76-92; 99-117; 129-147; 168-193; 199-218; 

PDB code: 1XQF_A
Observed 6-36; 43-69; 97-120; 124-149; 167-181; 197-218; 224-254; 257-273; 280-301; 313-333; 347-381; 
TMHindex 9-35; 46-65; 100-121; 124-139; 168-181; 197-219; 224-252; 259-275; 278-305; 314-338; 342-382; 
MEMBRAIN 9-33; 44-66; 96-118; 126-148; 164-181; 198-216; 225-249; 260-274; 277-301; 317-334; 349-380; 
THUMBU 12-30; 47-67; 97-115; 137-155; 165-180; 204-215; 231-245; 266-299; 319-337; 354-374; 
SOSUI 12-34; 44-66; 118-140; 162-183; 194-216; 225-247; 278-300; 318-340; 357-379; 
DAS_TMfilter 13-33; 45-66; 107-120; 123-148; 169-181; 202-212; 229-246; 276-299; 320-335; 358-374; 
TOP_PRED 11-31; 44-64; 100-120; 125-145; 161-181; 197-217; 227-247; 256-276; 282-302; 319-339; 356-376; 
TMHMM_2.0 10-32; 45-67; 98-120; 127-149; 164-183; 196-215; 225-247; 259-281; 285-302; 315-337; 352-374; 
Phobius 12-32; 44-64; 98-120; 127-149; 161-183; 195-214; 226-246; 258-275; 281-302; 314-334; 354-374; 

PDB code: 1YCE_A
Observed 2-46; 49-81; 
TMHindex 2-47; 49-82; 
MEMBRAIN 8-37; 55-83; 
THUMBU 65-80; 
SOSUI 5-27; 67-89; 
DAS_TMfilter 69-82; 
TOP_PRED 8-28; 69-89; 
TMHMM_2.0 9-31; 66-88; 
Phobius 69-88; 

PDB code: 1ZCD_A
Observed 12-30; 59-85; 95-116; 121-143; 150-175; 182-200; 205-218; 223-236; 247-271; 290-311; 327-350; 357-382; 
TMHindex 12-32; 59-90; 96-116; 128-145; 150-175; 182-199; 208-219; 226-236; 258-272; 285-316; 330-352; 357-378; 
MEMBRAIN 15-28; 63-77; 98-115; 131-144; 150-178; 183-199; 204-219; 225-235; 257-269; 285-312; 328-348; 363-379; 
THUMBU 12-30; 62-72; 96-114; 133-151; 173-191; 214-232; 258-272; 287-307; 330-346; 366-375; 
SOSUI 11-32; 58-79; 93-115; 126-148; 153-175; 181-202; 212-234; 253-274; 291-313; 327-349; 357-379; 
DAS_TMfilter 14-28; 65-77; 98-114; 134-176; 134-176; 183-199; 207-220; 226-236; 258-270; 285-312; 330-349; 365-374; 
TOP_PRED 12-32; 58-78; 95-115; 126-146; 154-174; 179-199; 220-240; 254-274; 282-302; 328-348; 360-380; 
TMHMM_2.0 7-29; 60-77; 94-116; 126-145; 152-174; 179-201; 206-237; 257-279; 291-313; 328-350; 357-379; 
Phobius 12-39; 59-79; 91-114; 126-145; 154-175; 181-200; 207-238; 258-276; 288-312; 324-351; 363-380; 

PDB code: 2A65_A
Observed 10-38; 40-71; 87-125; 165-184; 190-214; 240-267; 275-307; 336-370; 374-396; 398-425; 446-478; 482-514; 
TMHindex 7-35; 43-76; 82-125; 164-186; 196-216; 242-267; 290-300; 340-369; 376-393; 401-430; 441-470; 481-504; 
MEMBRAIN 14-27; 42-63; 77-123; 163-188; 196-218; 249-265; 277-304; 334-366; 378-400; 405-428; 445-471; 485-502; 
THUMBU 16-24; 42-62; 87-119; 167-182; 199-215; 249-261; 297-318; 333-359; 382-394; 411-425; 453-468; 484-501; 
SOSUI 6-28; 41-63; 88-110; 112-133; 164-186; 196-218; 243-265; 292-314; 340-362; 377-399; 407-429; 453-475; 483-504; 
DAS_TMfilter 43-60; 92-124; 165-184; 198-216; 247-264; 297-309; 337-358; 380-395; 409-427; 452-468; 485-503; 
TOP_PRED 9-29; 41-61; 91-111; 164-184; 194-214; 247-267; 291-311; 335-355; 377-397; 409-429; 449-469; 485-505; 
TMHMM_2.0 7-29; 39-61; 89-111; 165-187; 194-216; 243-265; 293-315; 335-357; 378-395; 405-427; 447-469; 484-503; 
Phobius 12-29; 41-61; 92-111; 166-185; 197-215; 243-268; 289-314; 342-367; 379-399; 405-427; 447-469; 481-503; 

PDB code: 2AHZ_A
Observed 21-45; 49-62; 73-103; 
TMHindex 22-46; 49-62; 73-103; 
MEMBRAIN 21-44; 51-74; 78-103; 
THUMBU 31-39; 81-100; 
SOSUI 1-20; 24-46; 81-103; 
DAS_TMfilter 27-40; 79-96; 
TOP_PRED 24-44; 50-70; 76-96; 
TMHMM_2.0 26-48; 78-100; 
Phobius 26-45; 78-100; 

PDB code: 2B2J_A
Observed 2-29; 35-64; 84-105; 113-138; 156-172; 186-208; 213-241; 245-261; 268-293; 300-320; 334-367; 
TMHindex 2-29; 37-63; 82-105; 114-130; 156-173; 186-208; 213-240; 246-263; 266-287; 301-320; 329-367; 
MEMBRAIN 7-29; 38-63; 86-107; 114-137; 146-170; 187-206; 213-239; 248-263; 266-289; 305-320; 338-366; 
THUMBU 10-25; 42-63; 90-103; 116-139; 154-164; 189-206; 223-234; 268-284; 344-363; 
SOSUI 7-29; 38-60; 62-84; 88-110; 113-135; 148-170; 182-203; 215-237; 258-280; 306-328; 343-365; 
DAS_TMfilter 9-26; 39-61; 93-106; 116-133; 154-167; 189-201; 227-237; 251-260; 270-286; 342-363; 
TOP_PRED 6-26; 39-59; 64-84; 87-107; 114-134; 152-172; 186-206; 220-240; 245-265; 269-289; 301-321; 340-360; 
TMHMM_2.0 6-28; 35-57; 87-109; 116-138; 153-172; 185-204; 219-238; 245-267; 272-289; 301-323; 338-360; 
Phobius 6-28; 40-59; 87-105; 117-138; 150-172; 184-204; 216-240; 247-265; 271-287; 299-319; 339-360; 

PDB code: 2B5F_A
Observed 39-64; 73-92; 101-110; 115-139; 160-182; 198-218; 222-234; 243-260; 
TMHindex 39-58; 73-94; 102-113; 115-138; 158-181; 195-217; 220-220; 248-258; 
MEMBRAIN 40-60; 72-95; 101-111; 117-141; 163-182; 195-218; 241-263; 
THUMBU 40-56; 72-97; 111-133; 200-215; 246-260; 
SOSUI 40-62; 70-92; 114-136; 163-185; 192-214; 240-262; 
DAS_TMfilter 41-60; 70-95; 105-135; 167-180; 197-215; 248-257; 
TOP_PRED 43-63; 71-91; 119-139; 164-184; 194-214; 241-261; 
TMHMM_2.0 40-62; 72-94; 115-137; 162-181; 194-216; 242-264; 
Phobius 37-60; 72-95; 115-137; 196-216; 243-264; 

PDB code: 2BBJ_A
Observed 293-312; 326-345; 
TMHindex 298-312; 332-345; 
MEMBRAIN 295-313; 327-347; 
THUMBU 299-313; 332-342; 
SOSUI 295-317; 328-347; 
DAS_TMfilter 297-311; 332-345; 
TOP_PRED 296-316; 328-348; 
TMHMM_2.0 296-318; 328-348; 
Phobius 296-316; 328-348; 

PDB code: 2BL2_A
Observed 11-46; 51-79; 87-122; 127-155; 
TMHindex 11-46; 51-79; 85-122; 129-156; 
MEMBRAIN 13-40; 55-80; 89-114; 127-150; 
THUMBU 10-23; 63-85; 92-102; 136-147; 
SOSUI 7-29; 63-85; 94-116; 131-153; 
DAS_TMfilter 14-23; 67-80; 138-151; 
TOP_PRED 10-30; 62-82; 89-109; 136-156; 
TMHMM_2.0 13-35; 55-77; 89-111; 131-153; 
Phobius 55-78; 90-111; 131-154; 

PDB code: 2BRD_A
Observed 9-31; 38-62; 77-100; 105-127; 134-157; 166-191; 203-226; 
TMHindex 11-31; 44-63; 79-100; 105-127; 133-159; 167-191; 215-226; 
MEMBRAIN 10-30; 43-63; 78-97; 107-127; 134-154; 172-191; 203-224; 
THUMBU 16-27; 49-65; 85-106; 126-155; 179-194; 202-217; 
SOSUI 10-32; 45-67; 77-99; 106-128; 136-158; 176-198; 203-224; 
DAS_TMfilter 14-28; 46-67; 88-102; 109-124; 138-156; 178-191; 203-223; 
TOP_PRED 8-28; 43-63; 82-102; 105-125; 137-157; 175-195; 203-223; 
TMHMM_2.0 10-29; 42-64; 79-101; 108-130; 135-157; 177-199; 
Phobius 12-29; 41-63; 83-101; 108-129; 135-156; 177-199; 205-224; 

PDB code: 2H8A_A
Observed 9-32; 62-95; 99-122; 128-147; 
TMHindex 9-32; 62-94; 100-123; 130-146; 
MEMBRAIN 13-33; 83-95; 101-117; 133-143; 
THUMBU 18-27; 106-117; 
SOSUI 
DAS_TMfilter 18-26; 85-93; 
TOP_PRED 11-31; 80-100; 128-148; 
TMHMM_2.0 10-32; 82-104; 130-148; 
Phobius 12-35; 82-110; 130-148; 

PDB code: 2HI7_B
Observed 14-36; 43-64; 71-96; 144-162; 
TMHindex 16-33; 46-65; 70-99; 144-162; 
MEMBRAIN 13-33; 39-64; 69-91; 140-164; 
THUMBU 18-60; 76-85; 142-160; 
SOSUI 12-34; 41-63; 144-165; 
DAS_TMfilter 16-38; 41-62; 72-80; 145-163; 
TOP_PRED 13-33; 48-68; 144-164; 
TMHMM_2.0 13-35; 45-64; 71-89; 145-162; 
Phobius 12-33; 45-64; 71-89; 145-166; 

PDB code: 2IRV_A
Observed 3-24; 56-79; 79-103; 109-127; 137-150; 161-178; 
TMHindex 2-24; 56-79; 79-104; 108-126; 137-153; 164-174; 
MEMBRAIN 6-21; 46-74; 79-103; 106-123; 132-156; 162-175; 
THUMBU 10-27; 51-70; 136-173; 
SOSUI 2-24; 47-69; 78-100; 102-123; 134-156; 159-180; 
DAS_TMfilter 8-22; 52-69; 83-94; 110-118; 136-153; 165-173; 
TOP_PRED 3-23; 51-71; 78-98; 102-122; 137-157; 
TMHMM_2.0 5-24; 44-66; 78-97; 101-123; 132-154; 159-181; 
Phobius 7-24; 44-69; 81-97; 103-121; 133-151; 157-176; 

PDB code: 2IUB_A
Observed 291-312; 327-349; 
TMHindex 310-312; 343-351; 
MEMBRAIN 304-322; 336-356; 
THUMBU 308-322; 341-351; 
SOSUI 304-326; 337-356; 
DAS_TMfilter 306-320; 341-354; 
TOP_PRED 305-325; 337-357; 
TMHMM_2.0 305-327; 337-357; 
Phobius 305-325; 337-357; 

PDB code: 2J7A_C
Observed 14-38; 
TMHindex 11-41; 
MEMBRAIN 13-32; 
THUMBU 19-29; 
SOSUI 14-34; 
DAS_TMfilter 16-31; 
TOP_PRED 15-35; 
TMHMM_2.0 13-32; 
Phobius 

PDB code: 2JO1_A
Observed 18-38; 
TMHindex 18-38; 
MEMBRAIN 19-36; 
THUMBU 18-36; 
SOSUI 16-37; 
DAS_TMfilter 16-38; 
TOP_PRED 17-37; 
TMHMM_2.0 15-37; 
Phobius 16-36; 

PDB code: 2NQ2_A
Observed 7-24; 57-87; 99-113; 119-138; 147-171; 199-213; 236-256; 265-274; 279-303; 311-329; 
TMHindex 6-26; 65-85; 98-114; 118-138; 146-169; 199-213; 236-254; 260-276; 280-299; 310-328; 
MEMBRAIN 8-29; 62-84; 100-118; 120-141; 148-170; 196-215; 238-262; 281-301; 307-327; 
THUMBU 13-26; 65-80; 103-136; 138-165; 197-215; 239-270; 286-296; 
SOSUI 7-29; 65-87; 93-115; 119-141; 149-171; 196-218; 239-261; 281-303; 308-329; 
DAS_TMfilter 10-27; 67-82; 107-139; 146-167; 198-215; 240-252; 287-295; 312-326; 
TOP_PRED 8-28; 66-86; 120-140; 146-166; 196-216; 240-260; 279-299; 308-328; 
TMHMM_2.0 10-32; 66-88; 108-139; 146-168; 198-220; 241-263; 309-328; 
Phobius 6-27; 66-87; 107-140; 147-171; 197-219; 240-267; 279-297; 309-328; 

PDB code: 2ONK_C
Observed 24-53; 67-101; 106-134; 150-177; 199-228; 252-273; 
TMHindex 28-50; 67-101; 106-134; 150-163; 201-214; 251-273; 
MEMBRAIN 23-58; 70-100; 110-136; 142-172; 203-236; 249-273; 
THUMBU 25-53; 77-96; 118-139; 150-163; 200-208; 217-237; 252-271; 
SOSUI 28-50; 75-97; 113-135; 148-170; 192-214; 221-243; 251-273; 
DAS_TMfilter 25-53; 74-98; 116-140; 149-165; 195-209; 224-237; 251-273; 
TOP_PRED 26-46; 80-100; 123-143; 148-168; 195-215; 221-241; 250-270; 
TMHMM_2.0 27-49; 78-100; 113-135; 150-167; 219-241; 251-273; 
Phobius 26-56; 76-100; 112-135; 147-167; 195-217; 223-241; 253-274; 

PDB code: 2PNO_A
Observed 5-33; 43-74; 75-100; 104-147; 
TMHindex 2-38; 38-74; 75-99; 105-148; 
MEMBRAIN 6-21; 59-77; 80-92; 108-132; 
THUMBU 10-24; 61-90; 109-135; 
SOSUI 5-27; 64-86; 116-138; 
DAS_TMfilter 7-23; 61-75; 77-89; 111-140; 
TOP_PRED 5-25; 58-78; 114-134; 
TMHMM_2.0 7-29; 67-89; 109-131; 
Phobius 67-89; 110-131; 

PDB code: 2Q7M_A
Observed 10-37; 48-77; 81-101; 116-138; 
TMHindex 9-37; 48-77; 80-102; 118-139; 
MEMBRAIN 7-25; 63-79; 84-97; 112-138; 
THUMBU 10-21; 67-86; 116-143; 
SOSUI 5-27; 67-89; 118-140; 
DAS_TMfilter 8-21; 67-78; 84-92; 116-139; 
TOP_PRED 5-25; 63-83; 118-138; 141-161; 
TMHMM_2.0 7-26; 71-93; 118-140; 
Phobius 7-26; 69-93; 114-137; 143-160; 

PDB code: 2QTS_A
Observed 19-45; 401-433; 
TMHindex 23-47; 407-433; 
MEMBRAIN 19-41; 410-431; 
THUMBU 23-42; 411-426; 
SOSUI 20-42; 
DAS_TMfilter 23-36; 416-425; 
TOP_PRED 19-39; 233-253; 408-428; 
TMHMM_2.0 20-42; 
Phobius 20-38;